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Publikationen Prof. Dr. Günther Weindl

2014-2018

2018

Heinbockel L, Weindl G, Martinez-de-Tejada G, Correa W, Sanchez-Gomez S, Bárcena-Varela S, Goldmann T, Garidel P, Gutsmann T, Brandenburg K (2018) Inhibition of lipopolysaccharide- and lipoprotein-induced inflammation by antitoxin peptide Pep19-2.5. Front Immunol. 9: 1704. doi: 10.3389/fimmu.2018.01704

Pfalzgraff A, Bárcena-Varela S, Heinbockel L, Gutsmann T, Brandenburg K, Martinez-de-Tejada G, Weindl G (2018) Antimicrobial endotoxin-neutralizing peptides promote keratinocyte migration via P2X7 receptor activation and accelerate wound healing in vivo. Brit J Pharmacol 175: 3581-93. doi: 10.1111/bph.14425

Grabowski M, Murgueitio MS, Bermudez M, Rademann J, Wolber G, Weindl G (2018) Identification of a pyrogallol derivative as a potent and selective human TLR2 antagonist by structure-based virtual screening. Biochem Pharmacol 154: 148-60. doi: 10.1016/j.bcp.2018.04.018

Pfalzgraff A, Brandenburg K, Weindl G (2018) Antimicrobial peptides and their therapeutic potential for bacterial skin infections and wounds. Front Pharmacol. 9: 281. doi: 10.3389/fphar.2018.00281

Su Q, Weindl G (2018) Glucocorticoids and Toll-like receptor 2 cooperatively induce acute-phase serum amyloid A. Pharmacol Res 128: 145-52. doi: 10.1016/j.phrs.2017.09.012

Bock S, Said A, Müller G, Schäfer-Korting M, Zoschke C, Weindl G (2018) Characterization of reconstructed human skin containing Langerhans cells to monitor molecular events in skin sensitization. Toxicol In Vitro 46: 77-85. doi: 10.1016/j.tiv.2017.09.019

2017

Grohmann L, Becker D, Rademann J, Ma N, Schäfer-Korting M, Weindl G (2017) Biotransformation of 2,4-toluenediamine in human skin and reconstructed tissues. Arch Toxicol 91: 3307-3316. doi: 10.1007/s00204-017-1954-5

Pfalzgraff A, Heinbockel L, Su Q, Brandenburg K, Weindl G (2017) Synthetic anti-endotoxin peptides inhibit cytoplasmic LPS-mediated responses. Biochem Pharmacol 140: 64-72. doi: 10.1016/j.bcp.2017.05.015

Su Q, Pfalzgraff A, Weindl G (2017) Cell type-specific regulatory effects of glucocorticoids on cutaneous TLR2 expression and signalling. J Steroid Biochem Mol Biol 171: 201-8. doi: 10.1016/j.jsbmb.2017.03.023

Su Q, Grabowski M, Weindl G (2017) Recognition of Propionibacterium acnes by human TLR2 heterodimers. Int J Med Microbiol 307: 108-12. doi: 10.1016/j.ijmm.2016.12.002

2016

Pfalzgraff A, Heinbockel L, Su Q, Gutsmann T, Brandenburg K, Weindl G (2016) Synthetic antimicrobial and LPS-neutralising peptides suppress inflammatory and immune responses in skin cells and promote keratinocyte migration. Sci Rep 6: 31577. doi: 10.1038/srep31577

Bock S, Pfalzgraff A, Weindl G (2016) Sphingosine 1-phospate differentially modulates maturation and function of human Langerhans-like cells. J Dermatol Sci 82: 9-17. doi: 10.1016/j.jdermsci.2016.01.002

Bock S, Murgueitio MS, Wolber G, Weindl G (2016) Acute myeloid leukaemia-derived Langerhans-like cells enhance Th1 polarization upon TLR2 engagement. Pharmacol Res 105: 44-53. doi: 10.1016/j.phrs.2016.01.016

Klionsky DJ, ..., Weindl G, ..., Zughaier SM (2016) Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition). Autophagy 12: 1-222. doi: 10.1080/15548627.2015.1100356

2015

Said A, Weindl G (2015) Regulation of dendritic cell function in inflammation. J Immunol Res. 2015: 743169. doi: 10.1155/2015/743169

Guenova E, Skabytska Y, Hoetzenecker W, Weindl G, Sauer K, Tham M, Kim KW, Park JH, Seo JH, Ignatova D, Cozzio A, Levesque MP, Volz T, Köberle M, Kaesler S, Thomas P, Mailhammer R, Ghoreschi K, Schäkel K, Amarov B, Eichner M, Schaller M, Clark RA, Röcken M, Biedermann T (2015) IL-4 abrogates TH17 cell-mediated inflammation by selective silencing of IL-23 in antigen-presenting cells. Proc Natl Acad Sci U S A 112: 2163-2168. doi: 10.1073/pnas.1416922112

Said A, Bock S, Müller G, Weindl G (2015) Inflammatory conditions distinctively alter immunological functions of Langerhans-like cells and dendritic cells in vitro. Immunology 144: 218-230. doi: 10.1111/imm.12363

2014

Said A, Bock S, Lajqi T, Müller G, Weindl G (2014) Chloroquine Promotes IL-17 Production by CD4+ T Cells via p38-Dependent IL-23 Release by Monocyte-Derived Langerhans-like Cells. J Immunol 193: 6135-6143. doi: 10.4049/jimmunol.1303276

Kumar S, Alnasif N, Fleige E, Kurniasih I, Kral V, Haase A, Luch A, Weindl G, Haag R, Schäfer-Korting M, Hedtrich S (2014) Impact of structural differences in hyperbranched polyglycerol-polyethylene glycol nanoparticles on dermal drug delivery and biocompatibility. Eur J Pharm Biopharm 88: 625-634. doi: 10.1016/j.ejpb.2014.10.014

Weindl G, Naglik JR, Moyes DL, Schaller M (2014) Mucosal Immunology in Candida albicans Infection. In: The Mycota, Vol. 12: Human Fungal Pathogens (2nd ed.), Kurzai O (Ed.), Springer Verlag, Berlin, pp. 161-176. doi: 10.1007/978-3-642-39432-4_9

Do N, Weindl G, Fleige E, Salwiczek M, Koksch B, Haag R, Schäfer-Korting M (2014) Core-multishell nanotransporters enhance skin penetration of the cell-penetrating peptide low molecular weight protamine. Polymer Adv Tech 25: 1337-1341. doi: 10.1002/pat.3362

Do N, Weindl G, Grohmann L, Salwiczek M, Koksch B, Korting HC, Schäfer-Korting M (2014) Cationic membrane-active peptides - anticancer and antifungal activity as well as penetration into human skin. Exp Dermatol 23: 326-331. doi: 10.1111/exd.12384

Eckl KM, Weindl G, Ackermann K, Küchler S, Casper R, Radowski M, Haag R, Hennies HC, Schäfer-Korting M (2014) Increased cutaneous absorption reflects impaired barrier function of reconstructed skin models mimicking keratinisation disorders. Exp Dermatol 23: 286-288. doi: 10.1111/exd.12366

Ali-von Laue C, Zoschke C, Do N, Lehnen D, Küchler S, Mehnert W, Blaschke T, Kramer KD, Plendl J, Weindl G, Korting HC, Hoeller Obrigkeit D, Merk HF, Schäfer-Korting M (2014) Improving topical non-melanoma skin cancer treatment: In vitro efficacy of a novel guanosine-analog phosphonate. Skin Pharmacol Physiol 27: 173-180. doi: 10.1159/000354118

Hamidi S, Schäfer-Korting M, Weindl G (2014) TLR2/1 and sphingosine 1-phosphate modulate inflammation, myofibroblast differentiation and cell migration in fibroblasts. Biochim Biophys Acta 1841: 484-494. doi: 10.1016/j.bbalip.2014.01.008

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